Human fungal pathogens a subject collection from Cold Spring Harbor perspectives in medicine

Machine generated contents note:Introduction and general principles and evolution of fungal pathogens. 1. The spectrum of fungi that infect humans. 2. Evolutionary perspectives on human fungal pathogens. 3. Sexual cycles, life cycles, and fungal disease. 4. Genetics and genomics of human fungal path...

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Weitere Verfasser: Casadevall, Arturo (BerichterstatterIn)
Format: UnknownFormat
Sprache:eng
Veröffentlicht: Cold Spring Harbor, NY Cold Spring Harbor Laboratory Press 2015
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Zusammenfassung:Machine generated contents note:Introduction and general principles and evolution of fungal pathogens. 1. The spectrum of fungi that infect humans. 2. Evolutionary perspectives on human fungal pathogens. 3. Sexual cycles, life cycles, and fungal disease. 4. Genetics and genomics of human fungal pathogens. 5. Fungal ploidy and parasexual cycles. Host immunity and fungal infection. 6. Adaptive immunity in defense against fungal pathogens. 7. Innate immunity in defense against fungal pathogens. 8. Genetics of human susceptibility to fungal infection. 9. Interactions of fungal pathogens with immune cells in the lung. Microbial virulence mechanisms. 10. Fungal biofilms, drug resistance and recurrent infection. 11. Fungal survival and replication in macrophages. 12. Morphogenesis in fungal pathogens. 13. Mechanisms of fungal tissue invasion and persistence in tissue. 14. Metabolism in fungal pathogenesis. Treatment strategies. 15. Fungal diagnostics. 16. Antifungal drug development.17. Fungal vaccines and immunotherapeutics. 18. Antifungal pharmacokinetics/pharmacodynamics. 19. Principles of management of yeasts and mould infections. 20. Antifungal clinical trials and guidelines : what we know and don't know. 21. Mechanisms of fungal drug resistance. Fungal pathogens. 22. Cryptococcus neoformans and Cryptococcus gattii. 23. Candida pathogenic species complex. 24. Aspergillus fumigatus and related pathogenic species. 25. Dimorphic human fungal pathogens. 26. Fungi on the skin : Dermatophytes and Malassezia. 27. Human fungal pathogens of Mucorales and Entomophthorales. 28. Black molds and other uncommon human fungal pathogens. 29. Pneumocystis. 30. The fungal mycobiome.
"Fungal infections affect millions of individuals worldwide. They a particular danger to immunocompromised individuals, such as those with HIV/AIDS, and invasive infections often have a mortality rate greater than 50%. This book examines our understanding of the biology of the major fungal pathogens, together with the host response, epidemiology of fungal diseases and current treatment strategies"--Provided by publisher
Beschreibung:"A subject collection from Cold Spring Harbor perspectives in medicine
Includes bibliographical references and index
Beschreibung:X, 577 S.
Ill.
27 cm
ISBN:9781621820758
978-1-62182-075-8