Multicomponent reactions 1 general discussion and reactions involving a carbonyl compound as electrophilic component

Relative reactivities of functional groups as the key to multicomponent reactions -- Reactions involving a carbonyl compound as electrophilic component: (1) with an amine or analogue as one nucleophilic component: third component 1,3-dicarbonyl compound (with ureas: Biginelli reaction) - third compo...

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Bibliographische Detailangaben
Weitere Verfasser: Müller, Thomas J. J. (BerichterstatterIn), Arévalo, M. J. (BerichterstatterIn)
Format: UnknownFormat
Sprache:eng
Veröffentlicht: Stuttgart u.a. Thieme 2013
Schriftenreihe:Science of synthesis 2013,5
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Zusammenfassung:Relative reactivities of functional groups as the key to multicomponent reactions -- Reactions involving a carbonyl compound as electrophilic component: (1) with an amine or analogue as one nucleophilic component: third component 1,3-dicarbonyl compound (with ureas: Biginelli reaction) - third component 1,3-dicarbonyl compound (with ammonia or amines: Hantzsch pyridine synthesis) - third component cyanide (Strecker and Strecker-type reactions) - third component enolizable carbonyl compound (Mannich reaction) - third component metal alkyl or aryl - third component alkyne - third component boronic acid (Petasis reaction)
Third component sulfur (Willgerodt-Kindler reaction) - third component phosphonate (Kabachnik-Fields reaction) -- (2) with an enamine as one component -- (3) with an isocyanide as one component: third component carboxylic acid (Passerini reaction) - further components carboxylic acid and amine (Ugi reaction) - modifications of the Ugi reaction -- (4) using a nitrile and sulfur as nucleophiles (Gewald reaction)
Beschreibung:Literaturangaben
Beschreibung:XXXII, 620 S.
graph. Darst.
255 mm x 170 mm
ISBN:3131668814
3-13-166881-4
9783131728616
978-3-13-172861-6
9783131668813
978-3-13-166881-3