Current challenges in personalized cancer medicine
Vertical pathway targeting in cancer therapy -- Histone deacetylases (HDACs) as mediators of resistance to apoptosis in melanoma and as targets for combination therapy with selective BRAF inhibitors -- Targeting the tumor stroma as a novel treatment strategy for breast cancer: shifting from the neop...
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| Format: | UnknownFormat |
| Sprache: | eng |
| Veröffentlicht: |
Amsterdam u.a.
Elsevier u.a
2012
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| Ausgabe: | 1. ed. |
| Schriftenreihe: | Advances in pharmacology
65 |
| Schlagworte: | |
| Online Zugang: | Inhaltsverzeichnis |
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Tag hinzufügen | Zusammenfassung: | Vertical pathway targeting in cancer therapy -- Histone deacetylases (HDACs) as mediators of resistance to apoptosis in melanoma and as targets for combination therapy with selective BRAF inhibitors -- Targeting the tumor stroma as a novel treatment strategy for breast cancer: shifting from the neoplastic cell-centric to a stroma-centric paradigm -- Targeting the metabolic microenvironment of tumors -- Targeted therapy for brain metastases -- Emerging strategies for targeting cell adhesion in multiple myeloma -- Targeting notch signaling for cancer therapeutic intervention -- Stem-like cells and therapy resistance in squamous cell carcinomas -- Targeting the tumor stroma as a novel therapeutic approach for prostate cancer -- Resistance to chemotherapy: short-term drug tolerance and stem cell-like subpopulations -- Intratumoral heterogeneity as a therapy resistance mechanism: role of melanoma subpopulations -- Chemoprevention of melanoma -- Whole genome and exome sequencing of melanoma: a step toward personalized targeted therapy -- Targeted therapy for gastric adenocarcinoma -- HSP90 inhibitors for cancer therapy and overcoming drug resistance -- Apoptosis in targeted therapy responses: the role of BIM. Vertical pathway targeting in cancer therapy -- Histone deacetylases (HDACs) as mediators of resistance to apoptosis in melanoma and as targets for combination therapy with selective BRAF inhibitors -- Targeting the tumor stroma as a novel treatment strategy for breast cancer: shifting from the neoplastic cell-centric to a stroma-centric paradigm -- Targeting the metabolic microenvironment of tumors -- Targeted therapy for brain metastases -- Emerging strategies for targeting cell adhesion in multiple myeloma -- Targeting notch signaling for cancer therapeutic intervention -- Stem-like cells and therapy resistance in squamous cell carcinomas -- Targeting the tumor stroma as a novel therapeutic approach for prostate cancer -- Resistance to chemotherapy: short-term drug tolerance and stem cell-like subpopulations -- Intratumoral heterogeneity as a therapy resistance mechanism: role of melanoma subpopulations -- Chemoprevention of melanoma -- Whole genome and exome sequencing of melanoma: a step toward personalized targeted therapy -- Targeted therapy for gastric adenocarcinoma -- HSP90 inhibitors for cancer therapy and overcoming drug resistance -- Apoptosis in targeted therapy responses: the role of BIM |
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| Beschreibung: | Literaturangaben |
| Beschreibung: | XVIII, 558 S. Ill., graph. Darst. |
| ISBN: | 9780123979278 978-0-12-397927-8 |