Drug disposition and pharmacokinetics : from principles to applications

Drug disposition and pharmacokinetics from principles to applications

Chemical introduction : sources, classification, and chemical properties of drugs -- Drug administration and distribution -- Drug elimination -- Elementary pharmacokinetics -- More complex and model independent pharmacokinetic models -- Kinetics of metabolism and excretion -- Further consideration o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: Curry, Stephen H. (VerfasserIn)
Weitere Verfasser: Whelpton, Robin (VerfasserIn)
Format: UnknownFormat
Sprache:eng
Veröffentlicht: Chichester u.a. Wiley-Blackwell c2011
Ausgabe:1. publ.
Schlagworte:
Pharmacokinetics > Biopharmaceutics > Drugs > Metabolism > Pharmaceutical Preparations > metabolism > Pharmakokinetik > Biopharmazie
Online Zugang:Cover
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Beschreibung
Zusammenfassung:Chemical introduction : sources, classification, and chemical properties of drugs -- Drug administration and distribution -- Drug elimination -- Elementary pharmacokinetics -- More complex and model independent pharmacokinetic models -- Kinetics of metabolism and excretion -- Further consideration of clearance, and physiological modelling -- Drug formulation : bioavailability, bioequivalence and controlled-release preparations -- Factors affecting plasma concentrations -- Pharmacogenetics and pharmacogenomics -- Developmental pharmacology and age-related phenomena -- Effects of disease on drug disposition -- Quantitative pharmacological relationships -- Simultaneous measurement of concentrations and effect, and pharmacokinetic/pharmacodynamic (PK/PD) modelling -- Drug monitoring in therapeutics -- Drug interactions -- Drug metabolism and pharmacokinetics in toxicology.
Beschreibung:Literaturangaben
Beschreibung:XIX, 365 S.
Ill., graph. Darst.
ISBN:9780470684467
978-0-470-68446-7