Handbook of drug screening
Key factors for successful high-throughput screening / John G. HoustonCritical components in high-throughput screening : challenges and new trends / Litao Zhang, Martyn N. Banks, and John G. Houston -- Hit-to-probe-to-lead optimization strategies : a biology perspective to conquer the valley of deat...
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| Weitere Verfasser: | , |
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| Format: | UnknownFormat |
| Sprache: | eng |
| Veröffentlicht: |
New York u.a.
Informa Healthcare
c2009
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| Ausgabe: | 2. ed. |
| Schriftenreihe: | Drugs and the pharmaceutical sciences
196 |
| Schlagworte: | |
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Tag hinzufügen | Zusammenfassung: | Key factors for successful high-throughput screening / John G. HoustonCritical components in high-throughput screening : challenges and new trends / Litao Zhang, Martyn N. Banks, and John G. Houston -- Hit-to-probe-to-lead optimization strategies : a biology perspective to conquer the valley of death / Anuradha Roy ... [et al.] -- Signal detection platforms for screening in drug discovery / Ramakrishna Seethala -- Proteomic analysis in drug discovery / Haiteng Deng, Yang Xu, and Linqi Zhang -- Screening and characterization of g-protein-coupled receptor ligands for drug discovery / Ge Zhang and Mary Ellen Cvijic Nuclear hormone receptor screening in drug discovery / Ramakrishna Seethala and Litao ZhangEmerging novel high-throughput screening technologies for cell-based assays / ILona Kariv ... [et al.] -- In vitro strategies for ion channel screening in drug discovery / Ravikumar Peri, Mark Bowlby, and John Dunlop -- Wheat from chaff : general and mechanistic triage of screening hits for enzyme targets / Mark R. Harpel -- Protein kinases and phosphatases / Pirthipal Singh -- MicroRNA strategies in drug discovery / Wishva B. Herath -- Strategies for screening of biologic therapeutics / Ian Foltz and Francesca Civoli Cryopreserved cells in functional cell-based HTS assays / Geetha Shankar and Kirk McMillanHigh-content screening with a special emphasis on cytotoxicity and cell health measurements Ralph J. Garippa and Ann F. Hoffman -- Effective application of drug metabolism and pharmacokinetics in drug discovery Sharon Diamond and Swanny Yeleswaram -- Compound management for drug discovery : an overview Moneesh Chatterjee and Martyn N. Banks -- Practical approach to quantitative high throughput screening Wei Zheng, Ke Liu, and James Inglese -- Enabling the large-scale analysis of quantitative high-throughput screening data Noel T. Southall ... [et al.] -- Application of nanobiotechnologies for drug discovery / K.K. Jain. Key factors for successful high throughput screening -- Critical components in high throughput screening : challenges and new trends -- Hit to probe to lead optimization strategies : a biology perspective to conquer the valley of death -- Signal detection platforms for screening in drug discovery -- Proteomic analysis in drug discovery -- Screening and characterization of g-protein-coupled receptor ligands for drug discovery -- Nuclear hormone receptor screening in drug discovery -- Emerging novel high-throughput screening technologies for cell-based assays -- In-vitro strategies for ion channel screening in drug discovery -- Wheat from chaff : general and mechanistic triage of screening hits for enzyme targets -- Protein kinases and phosphatases -- Micro rna strategies in drug discovery -- Strategies for screening of biologic therapeutics -- Cryopreserved cells in functional cell-based hts assays -- High-content screening with a special emphasis on cytotoxicity and cell health measurements -- Effective application of drug metabolism & pharmacokinetics in drug discovery -- Compound management for drug discovery : an overview -- Practical approach to quantitative high throughput screening -- Enabling the large scale analysis of quantitative high throughput screening data -- Application of nanobiotechnologies for drug discovery. |
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| Beschreibung: | Literaturangaben |
| Beschreibung: | XIII, 489 S. graph. Darst. |
| ISBN: | 9781420061680 978-1-4200-6168-0 1420061682 1-4200-6168-2 |