Systems biology properties of reconstructed networks
Preface; 1. Introduction; 2. Basic concepts in systems biology; Part I. Reconstruction of Biochemical Networks: 3. Metabolic networks; 4. Regulatory networks; 5. Signalling networks; Part II. Mathematical Representation of Reconstructed Networks: 6. Basic features of S; 7. Topological properties; 8....
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| Format: | UnknownFormat |
| Sprache: | eng |
| Veröffentlicht: |
Cambridge u.a.
Cambridge University Press
2006
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| Ausgabe: | 1. publ. |
| Schlagworte: | |
| Online Zugang: | Inhaltsverzeichnis Verlagsangaben Autorenbiografie Publisher description Table of contents Table of contents |
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Tag hinzufügen | Zusammenfassung: | Preface; 1. Introduction; 2. Basic concepts in systems biology; Part I. Reconstruction of Biochemical Networks: 3. Metabolic networks; 4. Regulatory networks; 5. Signalling networks; Part II. Mathematical Representation of Reconstructed Networks: 6. Basic features of S; 7. Topological properties; 8. Fundamental subspaces; 9. Null space of S; 10. The left null space of S; 11. The row and column spaces of S; Part III. Capabilities of Reconstructed Networks: 12. Dual causality; 13. Properties of solution spaces; 14. Sampling properties of solution spaces; 15. Finding functional states; 16. Parametric sensitivity; 17. Epilogue; Appendix A. Nomenclature and abbreviations; Appendix B. E. coli core metabolic network; Bibliography; Index. Genome sequences are now available that enable us to determine the biological components that make up a cell or an organism. The new discipline of systems biology examines how these components interact and form networks, and how the networks generate whole cell functions corresponding to observable phenotypes. This textbook, the first devoted to systems biology, describes how to model networks, how to determine their properties, and how to relate these to phenotypic functions. ... |
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| Beschreibung: | Literaturangaben und Literaturverz. S. 299 - 315 |
| Beschreibung: | XII, 322 S. Ill., graph. Darst. 27 cm |
| ISBN: | 0521859034 0-521-85903-4 9780521859035 978-0-521-85903-5 |