Integrated strategies for drug discovery using mass spectrometry
Miniaturized formats for efficient liquid chromatography mass spectrometry-based proteomics and therapeutic development / Gary A. ValaskovicMass spectrometry based drug screening assays for early phases in drug discovery / Marshall M. Siegel -- ESI-FTICR as a high throughput drug discovery platform...
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| Format: | UnknownFormat |
| Sprache: | eng |
| Veröffentlicht: |
Hoboken, NJ
Wiley-Interscience
2005
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| Schlagworte: |
Mass spectrometry
> Drugs
> Analysis
> High throughput screening (Drug development)
> High throughput screening Drug development
> Pharmaceutical Preparations
> analysis
> Drug Design
> Spectrum Analysis, Mass
> methods
> Chromatography, Liquid
> Pharmacokinetics
> Aufsatzsammlung
> Arzneimittelentwicklung
> Massenspektrometrie
> High throughput screening
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| Online Zugang: | Inhaltsverzeichnis Autorenbiografie Verlagsangaben Cover |
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| Zusammenfassung: | Miniaturized formats for efficient liquid chromatography mass spectrometry-based proteomics and therapeutic development / Gary A. ValaskovicMass spectrometry based drug screening assays for early phases in drug discovery / Marshall M. Siegel -- ESI-FTICR as a high throughput drug discovery platform / Kristin A. Sannes-Lowery -- Mass spectrometry based proteomic approaches for disease diagnosis and biomarker discovery / Thomas P. Conrads -- Metabonomic applications in toxicity screening and disease diagnosis / John P. Shockcor -- The central role of mass spectrometry in natural products discovery / Jeffrey R. Gilbert -- Application of mass spectrometry to compound library generation, analysis, and management / Xueheng Cheng -- A Combinatorial process for drug discovery / David S. Wagner -- Application of technological advances in biotransformation studies / Carmen L. Fernandez-Metzler -- Applications of mass spectrometry for the characterization of reactive metabolites of drugs in discovery / Jim Wang -- Advances in high-throughput quantitative drug discovery bioanalysis / Bradley L. Ackermann -- New strategies for the implementation and support of bioanalysis in a drug metabolism environment / Walter A. Korfmacher -- An integrated LC/MS strategy for preclinical candidate optimization / Jonathan L. Josephs -- New approaches for method development and purification in lead optimization / Yining Zhao -- High throughput metabolic and physicochemical property analysis / Edward H. Kerns -- Organ perfusion and mass spectrometry / C. Gerald Curtis -- Sample preparation for drug discovery bioanalysis / David A. Wells -- Automation / John D. Laycock. |
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| Beschreibung: | Literaturangaben |
| Beschreibung: | XVII, 550 S. Ill., graph. Darst. 24 cm |
| ISBN: | 9780471461272 978-0-471-46127-2 047146127X 0-471-46127-X |