Insulin & related proteins structure to function and pharmacology ; [this book contains contributions presented at the last of the Alcuin Symposia, held in April 2000, as a Festschrift to honour Prof. Axel Wollmer on the occasion of his retirement from the Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen]
Machine generated contents note: Foreword ix -- Contributors xi -- H. Zahn 1 -- How Insulin Came From Heidelberg To Aachen and Why It Took -- five Years. -- D. Brandenburg 7 -- Insulin at The German Wool Research Institute - Retrospect and Outlook -- G.G. Dodson and J.L. Whittingham 29 -- Insulin: S...
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| Format: | UnknownFormat |
| Sprache: | eng |
| Veröffentlicht: |
Dordrecht u.a.
Kluwer Academic Publ.
2002
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| Online Zugang: | Inhaltsverzeichnis Table of contents Table of contents Publisher description |
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Tag hinzufügen | Zusammenfassung: | Machine generated contents note: Foreword ix -- Contributors xi -- H. Zahn 1 -- How Insulin Came From Heidelberg To Aachen and Why It Took -- five Years. -- D. Brandenburg 7 -- Insulin at The German Wool Research Institute - Retrospect and Outlook -- G.G. Dodson and J.L. Whittingham 29 -- Insulin: Sequence, Structure and Function - A Story of Surprises -- U. Hassiepen, J. Stahl, B. Motzka and M. Federwisch 41 -- The Association/Dissociation equilibria of insulin in the presence of metal -- ions: A Fluorescence Energy Transfer and Circular Dichroism Study -- A. Wollmer and T. Milders 53 -- Self-association of Insulin Reconsidered -- I. A Scheme Based on Contact Surfaces -- T. Mulders and A. Wollmer 67 -- Self-association of Insulin Reconsidered -- II. Mathematical Description -- A. Wollmer 77 -- T-R Transition -- P. Kriiger 91 -- Comparison of Conformational Transitions in Proteins -- M.A. Weiss, Q.-X. Hua, W. Jia, S.H. Nakagawa, Y.-C. Chu, P.G. Katsoyannis 103 -- Activities of Insulin Analogues at Position A8 are Uncorrelated with -- Thermodynamic Stability -- R.H. Jones and F. Shojaee-Moradie 121 -- Relationships between the Structure of Insulin and its Physiological Effects -- P. De Meyts and J. Whittaker 131 -- Structure-Function Relationships of Insulin and Insulin-Like Growth -- Factor-I Receptor Binding -- C.W. Ward, T.P.J. Garrett, N.M. MCKer, L.G. Sparrow, M.J. Frenkel 151 -- Structural Relationships Between Members of the Insulin Receptor Family -- C. Kristensen and A.S. Andersen 165 -- Insulin Interaction with Minimized Receptors and Binding Proteins -- L. Plum, K. Giesen, R. Kluge, H.-G. Joost 177 -- Identification of Susceptibility Loci for Obesity, Insulin Resistance, and -- Hyperglycemia in a Backcross Model of New Zealand Obese (NZO) and -- Lean SJL MICE -- L. Pellegrini, D.F. Burke and T.L. Blundell 189 -- Activation Mechanism of fibroblast growth factor receptor tyrosine kinase -- revealed by crystal structure of fibroblast growth factor receptor ectodomain -- bound to fibroblast growth factor and heparin. -- J. Grotzinger 201 -- IL-6 type cytokine receptor complexes -- F. Bost, Y.-M. Yang, C. Liu, W. Charbono, N. Dean, R. McKay, X.-P. Lu, 213 -- O. Potapova, M. Pfahl and D. Mercola -- Inhibition of growth factor stimulated pathways for the treatment of prostate -- cancer -- R.W. Woody, C. Kiefl, N. Sreerama, Y. Lu, Y. Qiu and J. A. Shelnutt 233 -- Molecular Dynamics Simulations of Carbonmonoxy Myoglobin and -- Calculations of Heme Circular Dichroism -- Author Index 249 -- Keywords 251 |
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| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | xiv, 252 p graph. Darst |
| ISBN: | 1402006551 1-4020-0655-1 |