Untersuchungen zum Zusammenhang zwischen der Anzahl abgenommener Blutkultursets und der Positivitätswahrscheinlichkeit bei Patienten mit schwerer Sepsis und septischen Schock
Dissertation, Universitätsmedizin der Universität Greifswald, 2020
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Greifswald
2020
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Tag hinzufügen | Zusammenfassung: | Dissertation, Universitätsmedizin der Universität Greifswald, 2020 Blutkultur, Erreger, Primärfokus, Sepsis, schwere Sepsis, septischer Schock, Positivitätswahrscheinlichkeit The diagnosis of severe sepsis and septic shock is a challenge since only the interaction of serveral parameters can serve as an indication for a septic disease. Taking blood cultures is considered as the preferred diagnostic technique for severe sepsis and septic shock and it is an important tool to identify pathogens. The search of the causing pathogen serves as an adequate therapy initiation. Specific antibiotics can improve the patient´s outcome, shorten the hospital length of stay and can also avoid a rise in antimicrobial resistance. This study should show a context between the number of blood cultures and the positivity rate in patients with severe sepsis and septic shock who were examined by a guidline-based sepsis management. For this purpose, a total of 590 patients were examined in a retrospective data analysis. Data of two different time-groups were compared. The first focus was on the positivity rate for all included blood cultures. With the drawing of three blood cultures we could reach positivity rates of over 98% in both time-groups. The second focus was on the positivity rate for the different pathogens and the third focus was on the positivity rate for the different foci of infection. In conclusion taking three blood cultures reached the highest positivity rates for the most pathogens and foci. To sum up we could recommend the drawing of three blood cultures in patients with suspected severe sepsis and septic shock before a broad-spectrum antibiotic ... |
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| Beschreibung: | Literaturverzeichnis: Blatt 85-94 |
| Beschreibung: | 97 Blätter Diagramme (teilweise farbig) |