Microfluidics for the study of magnetotactic bacteria towards single-cell analysis

Dissertation, Universität Potsdam, 2020

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1. Verfasser: Cerdá Doñate, Elisa (VerfasserIn)
Körperschaft: Universität Potsdam (Grad-verleihende Institution)
Weitere Verfasser: Faivre, Damien (AkademischeR BetreuerIn), Robinson, Tom (AkademischeR BetreuerIn), Bald, Ilko (AkademischeR BetreuerIn), Baret, Jean-Christophe (AkademischeR BetreuerIn)
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Sprache:eng
Veröffentlicht: Potsdam 2020
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Zusammenfassung:Dissertation, Universität Potsdam, 2020
Magnetotactic bacteria comprise a heterogeneous group of Gram negative bacteria which share the ability to synthesise intracellular magnetic nanoparticles surrounded by a lipid bilayer, known as magnetosomes, which are arranged in linear chains. The bacteria exert a unique level of control onto the biomineralization of these nanoparticles, which is seen in the controlled size and shape they have. These characteristics have attracted great attention on understanding the process by which the bacteria synthesise the magnetosomes. Moreover, the magnetosome chain impart the bacteria with a net magnetic dipole which makes them susceptible to interact with magnetic fields and thus orient with the Earth’s magnetic field. This feature has attracted as well much interest to understand how the swimming motility of these microorganisms is affected by the presence of magnetic fields. Most of the studies performed in these bacteria so far have been conducted in the traditional manner using large populations of cells. Such studies have the ...
Beschreibung:X, 92 Seiten
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