Current trends and future developments on (bio-) membranes: membrane processes in the pharmaceutical and biotechnological field
3.5. Virus Purification by Bind and Elute Mode3.6. Flow through Mode for Virus Purification; 4. Tangential Flow Filtration for Virus Purification; 5. Conclusion and Future Trends; Acknowledgments; References; Chapter 4: Nanofiltration in the Pharmaceutical and Biopharmaceutical Technology; 1. Introd...
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| Format: | UnknownFormat |
| Sprache: | eng |
| Veröffentlicht: |
Amsterdam, Oxford, UK, Cambridge, MA
Elsevier
2019
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| Online Zugang: | Inhaltsverzeichnis |
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Tag hinzufügen | Zusammenfassung: | 3.5. Virus Purification by Bind and Elute Mode3.6. Flow through Mode for Virus Purification; 4. Tangential Flow Filtration for Virus Purification; 5. Conclusion and Future Trends; Acknowledgments; References; Chapter 4: Nanofiltration in the Pharmaceutical and Biopharmaceutical Technology; 1. Introduction; 2. Multistage Membrane Processes with Potential to Broaden Applications in Industry; 3. Membrane Cascades Operating in Batch Diafiltration Mode; 4. Membrane Cascades Operating in Continuous Mode; 5. Conclusions and Future Trends; References Chapter 2: Microfiltration in Pharmaceutics and Biotechnology1. Introduction; 2. Applications; 2.1. Cell Retention and Recycle; 2.2. Cell Harvesting and Broth Clarification; 2.3. Primary Separation of Product; 2.4. Microbe Removal; 3. Microfiltration Technologies; 3.1. Membranes and Modules; 3.2. Deadend Filtration; 3.3. Crossflow Filtration; 3.4. Monitoring and Control of Membrane Fouling; 4. Recent Advances; 4.1. Continuous Processing; 4.2. Alternating Tangential-Flow Filtration; 4.3. Single-Use Technologies; 5. Conclusions and Future Trends; Acknowledgments; References Chapter 3: Virus Removal and Virus Purification1. Introduction; 2. Virus Retentive Membranes for Virus Clearance; 2.1. Techniques to Characterize Virus Filtration Membranes; 2.2. Visualization Virus Retention within the Membrane; 2.3. Model Viruses and Surrogates; 2.4. Mechanistic Studies; 3. Membrane Adsorbers for Virus Clearance; 3.1. Virus Clearance with Membrane Adsorbers; 3.2. Anion Exchange (AEX) Membrane Adsorbers-Flow through Mode; 3.3. Cation Exchange (CEX) Membrane Adsorbers-Bind and Elute Mode; 3.4. Virus Purification with Membrane Adsorbers Chapter 5: Purification of New Biologicals Using Membrane-Based Processes1. Important Classes of Biologicals; 1.1. Antimicrobial Peptides; 1.2. Toxins; 1.3. Advanced Therapy Medicinal Products; 1.3.1. Virus-Based Products; 1.3.2. Cell-Based Products; 2. Membrane-Based Separation and Purification of Biologicals-Status, Trends, and Future Developments; 2.1. Perfusion for the Intensified Production of Biologicals in Animal Cells; 2.2. AMP Purification Based on Inclusion Bodies; 2.3. Toxin Purification and Concentration; 2.4. Clarification and Purification of Virus-Based Products Front Cover; Current Trends and Future Developments on (Bio-) Membranes: Membrane processes in the pharmaceutical and biotechnological field; Copyright; Contents; Contributors; Preface; Chapter 1: Ultra- and Microfiltration in Dairy Technology; 1. Introduction; 2. Applications of Ultrafiltration in Cascade Mode With Other Membrane Technologies; 2.1. UF Associated With MF; 2.2. UF Associated With NF/RO; 3. Protein Fractionation by Microfiltration; 4. ESL Milk Technology; 5. Ultrafiltration and Microfiltration in Diafiltration Mode; 6. Conclusion and Future Trends; References; Further Reading |
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| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | xvi, 349 Seiten Illustrationen |
| ISBN: | 9780128136065 978-0-12-813606-5 |