Complement therapeutics
Progress and trends in complement therapeutics -- Inhibition of the serine proteases of the complement system -- Role of MASP-1/3 in complement activation -- Membrane-bound complement regulatory proteins as biomarkers and potential therapeutic targets for SLE -- DAF as a therapeutic target for stero...
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| Weitere Verfasser: | , , |
| Format: | UnknownFormat |
| Sprache: | eng |
| Veröffentlicht: |
New York u.a.
Springer
2013
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| Schriftenreihe: | Advances in experimental medicine and biology
volume 735 |
| Schlagworte: | |
| Online Zugang: | Autorenbiografie Verlagsangaben Inhaltsverzeichnis http://digitale-objekte.hbz-nrw.de/webclient/DeliveryManager?pid=4674642&custom_att_2=simple_viewer |
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Tag hinzufügen | Zusammenfassung: | Progress and trends in complement therapeutics -- Inhibition of the serine proteases of the complement system -- Role of MASP-1/3 in complement activation -- Membrane-bound complement regulatory proteins as biomarkers and potential therapeutic targets for SLE -- DAF as a therapeutic target for steroid hormones: implications for host-pathogen interactions -- Targeting gC1qR domains for therapy against infection and inflammation -- Alternative C5a receptor function -- Effects of selective complement and CD14 inhibition on the E. coli-induced tissue factor mRNA upreglation, monocyte tissue factor expression, and tissue factor functional activity in human whole blood -- CR2-mediated targeting of complement inhibitors: bench-to-bedside using a novel strategy for site-specific complement modulation -- Paroxysmal nocturnal hemoglobinuria and the complement system: recent insights and novel anticomplement strategies -- Defective complement action and control defines disease pathology for retinal and renal disorders and provides a basis for new therapeutic approaches -- C3 glomerulonephritis/CFHR5 nephropathy is an endemic disease in Cyprus: clinical and molecular findings in 21 families -- Complement-targeted therapeutics in periodontitis -- Complement system activation in cardiac and skeletal muscle pathology: friend or foe? -- Innate immunity as orchestrator of bone marrow homing for hematopoietic stem/progenitor cells -- Complement-mediated microvascular injury leads to chronic rejection -- Targeting complement at the time of transplantation -- Evaluation of the blood compatibility of materials, cells, and tissues: basic concepts, test models, and practical guidelines -- Noninvasive detection of complement activation through radiologic imaging -- Highly multiplexed proteomic platform for biomarker discovery, diagnostics, and therapeutics -- Complement in action: an analysis of patent trends from 1976 through 2011. |
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| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | VIII, 320 Seiten Illustrationen |
| ISBN: | 9781461441175 978-1-4614-4117-5 146144117X 1-4614-4117-X |