Basic neurochemistry principles of molecular, cellular and medical neurobiology
Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology, the outstanding and comprehensive classic text on neurochemistry, is now newly updated and revised in its Eighth Edition. For more than forty years, this text has been the worldwide standard for information on the bio...
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| Format: | UnknownFormat |
| Sprache: | eng |
| Veröffentlicht: |
Amsterdam, Boston, Heidelberg, London
Elsevier, Academic Press
2012
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| Ausgabe: | 8th edition |
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| Online Zugang: | Verlagsangaben |
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Tag hinzufügen | Zusammenfassung: | Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology, the outstanding and comprehensive classic text on neurochemistry, is now newly updated and revised in its Eighth Edition. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences. The text has evolved, as intended, with the science. It is also an excellent source of current information on basic biochemical and cellular processes in brain function and neurological diseases for continuing medical education and qualifying examinations. This text continues to be the standard reference and textbook for exploring the translational nature of neuroscience, bringing basic and clinical neuroscience together in one authoritative volume. Our book title reflects the expanded attention to these links between neurochemistry and neurologic disease. This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from: Intracellular trafficking; Stem cells, adult neurogenesis, regeneration; Lipid messengers; Expanded coverage of all major neurodegenerative and psychiatric disorders; Neurochemistry of addiction; Neurochemistry of pain; Neurochemistry of hearing and balance; Neurobiology of learning and memory; Sleep; Myelin structure, development, and disease; Autism; and Neuroimmunology. The new edition features: * Completely updated text with new authors and material, and many entirely new chapters * Over 400 fully revised figures in splendid color * 61 chapters covering the range of cellular, molecular and medical neuroscience * Translational science boxes emphasizing the connections between basic and clinical neuroscience * Companion website at http://elsevierdirect.com/companions/9780123749475 Part I: Cellular Neurochemistry and Neural Membranes Cell Biology of the Nervous System Cell Membrane Structures and Functions Membrane Transport Electrical Excitability and Ion Channels Lipids The Cytoskeleton of Neurons and Glia Intracellular Trafficking Axonal Transport Cell Adhesion Molecules Myelin Structure and Biochemistry Energy Metabolism of the Brain PART II: Intercellular Signaling Synaptic Transmission and Cellular Signaling: An Overview Acetylcholine Catecholamines Serotonin Histamine Glutamate and Glutamate Receptors GABA Purinergic Signaling Peptides PART III: Intracellular Signaling G Proteins Cyclic Nucleotides in the Nervous System Phosphoinositides Calcium Serine and Threonine Phosphorylation Tyrosine Phosphorylation Transcription Factors in the Central Nervous System PART IV: Growth, Development and Differentiation Development of the Nervous System Growth Factors Stem Cells in the Nervous System Formation and Maintenance of Myelin Axonal Growth in the Adult Mammalian Nervous System PART V: Cell Injury and Inflammation Molecular Mechanisms and Consequences of Immune and Nervous System Reactions Neuroinflammation Brain Ischemia and Reperfusion: Cellular and Molecular Mechanisms in Stroke Injury Lipid Mediators: Eicosanoids, Docosanoids and Platelet-Activating Factor Apoptosis and Necrosis PART VI: Inherited and Neurodegenerative Diseases Peripheral Neuropathy Diseases Involving Myelin The Epilepsies: Phenotypes and Mechanisms Genetics of Neurodegenerative Diseases Disorders of Amino Acid Metabolism Inborn Metabolic Defects of Lysosomes, Peroxisomes, Carbohydrates, and Fatty Acids and Mitochondria Disorders of Muscle Excitability Motor Neuron Diseases Neurobiology of Alzheimer's Disease Synucleinopathies and Tauopathies Cellular and Molecular Basis of Neurodegeneration in the CAG-Polyglutamine Repeat Diseases Neurotransmitters and Disorders of the Basal Ganglia Molecular Basis of Prion Diseases PART VII: Sensory Transduction Molecular Biology of Vision Molecular Biology of Olfaction and Taste Molecular Biology of Hearing and Balance Pain PART VIII: Neural Processing and Behavior Endocrine Effects on the Brain and Their Relationship to Behavior Learning and Memory The Neurochemistry of Sleep and Wakefulness The Neurochemistry of Schizophrenia The Neurochemistry of Autism Neurobiology of Severe Mood and Anxiety Disorders Addiction -- Cell biology of the nervous system -- Cell membrane structures and functions -- Membrane transport -- Electrical excitability and ion channels -- Lipids -- The cytoskeleton of neurons and glia -- Intracellular trafficking -- Axonal transport -- Cell adhesion molecules -- Myelin structure and biochemistry -- Energy metabolism of the brain -- Synaptic transmission and cellular signaling: an overview -- Acetylcholine -- Catecholamines -- Serotonin -- Histamine -- Glutamate and glutamate receptors -- GABA -- Purinergic signaling -- Peptides -- G proteins -- Cyclic nucleotides in the nervous system -- Phosphoinositides -- Calcium -- Serine and threonine phophorylation -- Tyrosine phosphorylation -- Transcription factors in the central nervous system -- Development of the nervous system -- Growth factors -- Stem cells in the nervous system -- Formation and maintenance of myelin -- Axonal growth in the adult mammalian nervous system: regeneration and compensatory plasticity -- Molecular mechanisms and consequences of immune and nervous system interactions -- Neuroinflammation -- Brain ischemia and reperfusion: cellular and molecular mechanisms in stroke injury -- Lipid mediators: eicosanoids, docosanoids and platelet-activating factor -- Apoptosis and necrosis -- Peripheral neuropathy: neurochemical and molecular mechanisms -- Diseases involving myelin -- The epilepsies: phenotypes and mechanisms -- Genetics of neurodegenerative diseases -- Disorders of amino acid metabolism -- Inborn metabolic defects of lysosomes, peroxisomes, carbohydrates, fatty acids and mitochondria -- Disorders of muscle excitability -- Motor neuron diseases -- Neurobiology of Alzheimer's disease -- Synucleinopathies and tauopathies -- Cellular and molecular basis of neurodegeneration in the CAG-polyglutamine repeat diseases -- Neurotransmitter and disorders of the basal ganglia -- Molecular basis of prion diseases -- Molecular biology of vision -- Molecular basis of olfaction and taste -- Molecular biology of hearing and balance -- Pain -- Endocrine effects and the brain and their relationship to behavior -- Learning and memory -- The neurochemistry of sleep and wakefulness -- The neurochemistry of schizophrenia -- The neurochemistry of autism -- Neurobiology of severe mood and anxiety disorders -- Addiction |
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| Beschreibung: | Literaturangaben |
| Beschreibung: | xxiv, 1096 Seiten Illustrationen, Diagramme |
| ISBN: | 9780123749475 978-0-12-374947-5 |