Molecular mechanisms behind interindividual differences in cytochrome P450 expression implications for pharmacokinetics and toxicity of drugs

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Bibliographische Detailangaben
Veröffentlicht in:	Molecular investigation of metabolism and transport of drugs - from animal to human tissue
1. Verfasser:	Ingelman-Sundberg, Magnus (VerfasserIn)
Format:	UnknownFormat
Sprache:	eng
Veröffentlicht:	2003
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Titel	Jahr	Verfasser
Molecular mechanisms of multidrug transporters in prokaryotic and eukaryotic cells	2003
Influence of oestrogens on billiary bile acid pattern in ovariectomized rats	2003
HK-2-Cells - a suitable model to investigate organic anion transport ?	2003
The V79 cell batteryTM : an analytical tool for predicting drug metabolism dependent toxicity for humans	2003	Doehmer, Johannes
The effect of the coadministration of different inducers on the expression of CYP and conjugating enzymes	2003
The high affinity sodium-dependent dicarboxylate transporter from winter flounder kidney plays an important role in renal detoxification by translocation of the antidote 2,3-dimercaptosuccinate for mercury	2003
Role of lysosomal trapping in the cellular and body distribution of drugs	2003	Daniel, Wladyslawa Anna
Biotransformation and membrane transport in nephrotoxicity	2003	Dekant, Wolfgang
Transport and ex vivo stimulation of renal uptake of anticancer drugs (Methotrexate, Cisplatin, Topotecan [Hycamtin], Raltitrexed [Tomudes]) by Dexamethasone, T3 or EGF in human and in rat kidney tissue and in human renal cell carcinoma (RCC)	2003
Metabolic formation, distribution, and toxicological effects of reactive sulfuric acid esters	2003
Instability and aggregation promotes high transfection activities of peptide/protein complexes with DNA	2003
Identification of specific substrates for some multispecific organic anion transporting polypeptides	2003
Phenol and hydroquinone induce gene mutations in V79-derived cells expressing human xenobiotic-metabolizing enzymes	2003
Differential interactions of newly synthesized fomocaine derivatives with the cytochrome P450 system in vitro	2003
In Vitro investigations on the interactions of different fomocaine metabolites with rat microsomal cytochrome P450	2003
Albumin strongly prolongs the lifespan of chemically reactive sulphuric acid esters and affects their biological activities in the rat	2003	Ma, Lan
The renal type IIa Na/Pi-cotransporter : structure	2003
From transport studies to drugs : liver-targeting with bile acids. What we have learned and outlook on oligodeoxynucleotides	2003	Petzinger, Ernst
Endogenous substrates of the organic anion transporter 1 (OAT1) in kidneys and eyes : anionic metabolites of neurotransmitters	2003	Bahn, Andrew
If there exists correspondence between similarity of substrates and protein sequences in cytochrome P450 superfamily	2003

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