Pharmacological investigations on muscarinic receptor subtypes : development of the isolated rat duodenum (M3) and rabbit anococcygeus muscle (M2 and M4) as novel muscarinic receptor (subtype) models and pharmacological characterization of the M4-selective muscarinic antagonist PD102807 as well as delineation of structure activity relationships of muscarinic antagonists related to trihexyphenidyl and hexahydro-difenidol with regard of stereochemical aspects

Pharmacological investigations on muscarinic receptor subtypes development of the isolated rat duodenum (M3) and rabbit anococcygeus muscle (M2 and M4) as novel muscarinic receptor (subtype) models and pharmacological characterization of the M4-selective muscarinic antagonist PD102807 as well as delineation of structure activity relationships of muscarinic antagonists related to trihexyphenidyl and hexahydro-difenidol with regard of stereochemical aspects

Zugl.: Frankfurt (Main), Univ., Diss., 1998

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Bibliographische Detailangaben
1. Verfasser: Gross, Jan (VerfasserIn)
Format: UnknownFormat
Sprache:eng
Veröffentlicht: Aachen Shaker 1999
Ausgabe:Als Ms. gedr
Schriftenreihe:Berichte aus der Pharmazie
Schlagworte:
Hochschulschrift > Muscarinrezeptor > Pharmakologischer Antagonist > Struktur-Aktivitäts-Beziehung > Stereochemie > Tiermodell
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